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BioViotica
Benadrostin
90
CHF
CHF 90.00
In stock
BVT-0079-C500500 µgCHF 90.00
BVT-0079-M0011 mgCHF 145.00
| Product Details | |
|---|---|
| Synonyms | 8-Hydroxy-2H-1,3-benzoxazine-2,4(3H)-dione |
| Product Type | Chemical |
| Properties | |
| Formula |
C8H5NO4 |
| MW | 179.1 |
| CAS | 117241-60-8 |
| RTECS | DM3130000 |
| Source/Host Chemicals | Isolated from Streptomyces rubiguiosohelvolus Gö66. |
| Purity Chemicals | ≥98% (HPLC; NMR) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in DMSO, methanol or chloroform. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | BQIRLGRTNUTGAT-UHFFFAOYSA-N |
| Smiles | OC1=CC=CC2=C1OC(=O)NC2=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Poly(ADP-ribose) polymerase (PARP) inhibitor.
Product References
- Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physicochemical properties and biological activities: T. Aoyagi, et al.; J. Antibiot. 41, 1009 (1988)
- Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination: S. Yoshida, et al.; J. Antibiot. 41, 1015 (1988)
- Effects of benadrostin, a poly(ADP-ribose) polymerase inhibitor, on apoptosis of HL-60 induced by 5-azacytidine: H. Tobe, et al.; Biosci. Biotechnol. Biochem. 61, 1603 (1997)
- New potent DPPH radical scavengers from a marine-derived actinomycete strain USF-TC31: Y. Sugiyama, et al.; Biosci. Biotechnol. Biochem. 73, 2731 (2009)
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