Saquayamycin B1

CHF 130.00
In stock
BVT-0382-C500500 µgCHF 130.00
BVT-0382-M0011 mgCHF 200.00
BVT-0382-M0055 mgCHF 600.00
 
More Information
Product Details
Product Type Chemical
Properties
Formula C31H32O12
MW 596.6
CAS 99260-68-1
Source/Host Chemicals Isolated from Streptomyces nodosus.
Purity Chemicals ≥98% (HPLC)
Appearance Orange powder.
Solubility Soluble in DMSO, methanol or chloroform.
Identity Determined by 1H-NMR and UV.
Declaration Manufactured by BioViotica.
InChi Key CTSPXNCFVRSKKD-IGVHUSDSSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Store solutions at -20°C in the dark.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Angucycline antibiotic.
  • Antibacterial.
  • Antitumor compound.
  • Active against Gram-positive bacteria and P388 leukaemia cells.
  • Farnesyl-protein transferase inhibitor.
  • Inhibitor of nitric oxide synthase (NOS) (shown for Saquayamycin A1).
Product References
  1. Saquayamycins, new aquayamycin-group antibiotics: T. Uchida, et al.; J. Antibiot. 38, 1171 (1985)
  2. Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992) (Review)
  3. Isolation of novel saquayamycins as inhibitors of farnesyl-protein transferase: R. Sekizawa, et al.; J. Antibiot. 49, 487(1996)
  4. Identification of inhibitors of inducible nitric oxide synthase from microbial extracts: A. A. Khisal, et al.; J. Antibiot. 53, 496 (2000)
  5. Moromycins A and B: M. S. Abdelfattah, et al.; J. Nat. Prod. 71, 1569 (2008)
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