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Albocycline
115
CHF
CHF 115.00
In stock
BVT-0429-M0011 mgCHF 115.00
| Product Details | |
|---|---|
| Synonyms | Ingramycin; Antibiotic SR 2077; Antibiotic TA 2407 |
| Product Type | Chemical |
| Properties | |
| Formula |
C18H28O4 |
| MW | 308.4 |
| CAS | 25129-91-3 |
| Source/Host Chemicals | Isolated from Streptomyces sp. S1168. |
| Purity Chemicals | ≥98% (HPLC, NMR) |
| Appearance | Yellowish oil. |
| Solubility | Soluble in DMSO, methanol, dichloromethane or acetone. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | BYWWNDLILWPPJP-VHONNXCJSA-N |
| Smiles | CO[C@H]1\C=C\[C@@](C)(O)\C=C\C(=O)O[C@H](C)[C@@H](C)CC\C=C1/C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- 14-Membered macrolide without sugar moieties.
- Antibiotic. Selective mainly against staphylococci (incl. MRSA).
- Inhibitor of prolyl endopeptidase.
- Insecticidal activity.
- Inhibitor of nicotinic acid (nicotinate; NA) biosynthesis.
Product References
- Studies on a new antibiotic, albocycline. I. Isolation, purification and properties: N. Nagahamam, et al.; J. Antibiot. 5, 261 (1967)
- Mode of action of albocycline, an inhibitor of nicotinate biosynthesis: F. Reusser; J. Bact. 100, 11 (1969)
- Albocycline: structure determination by x-ray crystallography: R.C. Thomas & C.G. Chidester; J. Antibiot. 35, 1658 (1982)
- Biosynthesis of albocycline: origin of the carbon skeleton: A. Taddei & A. Zeeck; J. Antibiot. 50, 526 (1997)
- Albocycline- and carbomycin-type macrolides, inhibitors of human prolyl endopeptidases: C. Christner, et al.; J. Antibiot. 51, 368 (1998)
- New structural scaffold 14-membered macrocyclic lactone ring for selective inhibitors of cell wall peptidoglycan biosynthesis in Staphylococcus aureus: N. Koyama, et al.; J. Antibiot. 66, 303 (2013)
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