Chaetoglobosin F

CHF 220.00
In stock
BVT-0461-M0011 mgCHF 220.00
BVT-0461-M0055 mgCHF 660.00
 
More Information
Product Details
Synonyms (21,22-Dihydro,19-ketone,20β-alcohol)-chaetoglobosin A
Product Type Chemical
Properties
Formula C32H38N2O5
MW 530.7
CAS 55945-75-0
Source/Host Chemicals Isolated from Chaetomium sp.
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Off-white solid.
Solubility Soluble in DMSO, acetone or dichloromethane. Poorly soluble in methanol. Insoluble in water.
Identity Determined by 1H-NMR and MS.
Declaration Manufactured by BioViotica.
InChi Key KTFGDHPTDQFFRL-WSLWJRNMSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Cytochalasan mycotoxin, derivative of chaetoglobosin A (Prod. No. BVT-0092).
  • Phytotoxic.
  • Cytotoxic against HCT116 (human colon cancer cells).
  • Antibacterial (Ps. aeruginosa).
  • Anti-inflammatory and immunomodulatory compound.
Product References
  1. Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation, and some cytological effects of chaetoglobosin A-J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1609 (1982)
  2. Chaetoglobosins, cytotoxic 10-(indol-3yl)-[13]cytochalasans from Chaetomium spp. III. Structures of chaetoglobosins C, E, F, G, and J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1629 (1982)
  3. Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019: G. Ding, et al.; J. Nat. Prod. 69, 302 (2006)
  4. Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01: S. Thohinung, et al.; Arch. Pharm. Res. 33, 1135 (2010)
  5. Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum: J. Zhang, et al.; Planta Med. 76, 1910 (2010)
  6. New azaphilones from Chaetomium globosum isolated from the built environment: D.R. McMullin, et al.; Tetrahedron Lett. 54, 568 (2013)
  7. Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway: C. Hua, et al.; Immunobiology 218, 292 (2013)
  8. Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment: D.R. Mcmullin, et al.; Mycotoxin Res. 29, 47 (2013)
  9. Production of an antimicrobial cytochalasan by an endophytic Chaetomium globosum HYML55 from Hypericum mysorense and its RNA secondary structure analysis: P. Samaga, et al.; Chem. Ecology 30, 566 (2014)
  10. Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities: H. Li, et al.; J. Agr. Food Chem. 62, 3734 (2014)

 

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