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BioViotica
Piperafizine B
130
CHF
CHF 130.00
In stock
BVT-0446-C500500 µgCHF 130.00
BVT-0446-M0011 mgCHF 215.00
| Product Details | |
|---|---|
| Synonyms | 3,6-Dibenzylidene-2,5-piperazinedione; 3,6-Dibenzylidene-2,5-dioxopiperazine; 3,6-Bis(phenylmethylene)-2,5-piperazinedione |
| Product Type | Chemical |
| Properties | |
| Formula |
C18H14N2O2 |
| MW | 290.3 |
| CAS | 74720-33-5 |
| Source/Host Chemicals | Isolated from Streptomyces thioluteus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Light yellow solid. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR and 13C-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | RFSUEJIDSYCCLL-UKVBVZPVSA-N |
| Smiles | O=C1N\C(=C/C2=CC=CC=C2)C(=O)N\C1=C\C1=CC=CC=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Diketopiperazine derivative. Analog of Piperafizine A.
- Potentiator of vincristine cytotoxicity.
Product References
- The production of 3-benzylidene-6-isobutylidene-2,5-dioxopiperazine, 3,6-dibenzylidene-2,5-dioxopiperazine,3-benzyl-6-benzylidene-2,5-dioxopiperazine, and 3,6-dibenzyl-2,5-dioxopiperazine by a variant of Streptomyces noursei: R. Brown, et al.; J. Org. Chem. 30, 277 (1960)
- α,β-unsaturated carboxylic acid derivatives. Part 18. Syntheses of geometric isomers of 3,6-dibenzylidene and 3-p-anisylidene-6-benzylidene-2,5-piperazinedions: C. Shin, et al.; J. Chem. Soc. Perkin Trans. 1, 419 (1980)
- Molecular and electronic structure of the dehydroalanine derivatives: the cyclicdipeptide of dehydrophenylalanine: D. Ajo, et al.; Tetrahedron 41, 5543 (1985)
- Piperafizines A and B, potentiators of cytotoxicity of vincristine: H. Kamei, et al.; J. Antibiot. 43, 1018 (1990)
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