Capsaicin

CHF 57.00
In stock
CDX-C0157-M05050 mgCHF 57.00
CDX-C0157-M250250 mgCHF 230.00
CDX-C0157-G0011 gCHF 485.00
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Product Details
Synonyms 8-Methyl-N-vanillyl-trans-6-nonenamide; N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide; NSC 56353
Product Type Chemical
Properties
Formula C18H27NO3
MW 305.41
CAS 404-86-4
Source/Host Chemicals Synthetic.
Purity Chemicals ≥95% (HPLC)
Appearance White crystalline solid.
Solubility Soluble in ethanol, benzene, ether or chloroform.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key YKPUWZUDDOIDPM-SOFGYWHQSA-N
Smiles COC1=C(O)C=CC(CNC(=O)CCCC\C=C\C(C)C)=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1; TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. It has been shown to have antinociceptive, anti-inflammatory, anti-obesity, neuroprotective and anticancer effects.

Product References

(1) P.G. Hoffman, et al.; J. Agric. Food Chem. 31, 1326 (1983) | (2) P.M. Gannett, et al.; J. Org. Chem. 53, 1064 (1988) | (3) B. Lynn; Pain 41, 61 (1990) | (4) P. Holzer; Adv. Exp. Med. Biol. 298, 3 (1991) | (5) Y.J. Surh & S.S. Lee; Life Sci. 56, 1845 (1995) | (6) M.J. Caterina, et al.; Nature 389, 816 (1997) | (7) S.C. Pingle, et al.; Handb. Exp. Pharmacol. 179, 155 (2007) | (8) S.J. Conway; Chem. Soc. Rev. 37, 1530 (2008) | (9) F.W. Leung; Prog. Drug Res. 68, 171 (2014) | (10) Y. Deng, et al.; Autoimmun. Rev. (2016)

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