1-(4'-Carboxybutyl)-3,7-dimethylxanthine

CHF 111.00
In stock
CDX-C0312-M01010 mgCHF 111.00
CDX-C0312-M02525 mgCHF 223.00
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Product Details
Synonyms 2,3,6,7-Tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purine-1-pentanoic acid DB-dmx
Product Type Chemical
Properties
Formula C12H16N4O4
MW 280.28
CAS 38975-44-9
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (HPLC)
Appearance White powder.
Solubility Soluble in ethyl acetate.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key JDMFPLGXRUJOTC-UHFFFAOYSA-N
Smiles CN1C=NC2=C1C(=O)N(CCCCC(O)=O)C(=O)N2C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-α cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the β-2 integrin CD11b/CD18.

Product References

(1) S. Hayashi, et al.; Chem. Pharm. Bull. 24, 1384 (1976) | (2) T.A. Bryce, et al.; J. Chromatogr. 344, 397 (1985) | (3) G.W. Sullivan, et al.; Infect. Immun. 56, 1722 (1988) | (4) M. Fantin, et al.; Eur. J. Pharmacol. 301, 535 (2006) | (5) M. Magnusson, et al.; Eur. J. Pharmacol. 290, 581 (2008)

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