FGF-19 (human) (rec.) (His)

CHF 230.00
In stock
CHI-AG-40A-0111-C01010 µgCHF 230.00
CHI-AG-40A-0111-C05050 µgCHF 490.00
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Product Details
Synonyms Fibroblast Growth Factor 19
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

The extracellular domain of human FGF-19 (aa 25-216) is fused at the C-terminus to a His-tag.

Crossreactivity Human
MW ~22kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Endotoxin Content <0.06EU/μg purified protein (LAL test).
Reconstitution 10µg vial: Reconstitute with 100 µl sterile water to a concentration of 0.1mg/ml.
50µg vial: Reconstitute with 50 µl sterile water to a concentration of 1mg/ml.
Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in 1x PBS.
Other Product Data

UniProt link AAH17664.1: FGF-19 (human)

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

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