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IL-33R (human):Fc (human) (rec.)
390
CHF
CHF 390.00
In stock
CHI-HF-21033R-C05050 µgCHF 390.00
| Product Details | |
|---|---|
| Synonyms | Interleukin-33 Receptor; IL1RL1; DER4; ST2 |
| Product Type | Protein |
| Properties | |
| Source/Host | CHO cells |
| Sequence |
The extracellular domain of human IL-33R [ST2] (aa 19-328) is fused to the N-terminus of the Fc region of human IgG1. |
| Crossreactivity | Human |
| Biological Activity |
Measured by its ability to bind recombinant human IL-33 in a functional ELISA. |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | <0.06EU/μg protein (LAL test; Lonza). |
| Reconstitution |
Reconstitute in 50µl sterile water. Add 1X PBS to the desired protein concentration. |
| Formulation | Lyophilized from 0.2μm-filtered solution in PBS. |
| Protein Negative Control | |
| Other Product Data |
NCBI reference AAH30975.1: IL-33R (human) |
| Declaration | Manufactured by Chimerigen. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
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