IL-33R (human):Fc (human) (rec.)

CHF 380.00
In stock
CHI-HF-21033R-C05050 µgCHF 380.00
More Information
Product Details
Synonyms Interleukin-33 Receptor; IL1RL1; DER4; ST2
Product Type Protein
Properties
Source/Host CHO cells
Sequence

The extracellular domain of human IL-33R [ST2] (aa 19-328) is fused to the N-terminus of the Fc region of human IgG1.

Crossreactivity Human
Biological Activity

Measured by its ability to bind recombinant human IL-33 in a functional ELISA.

Purity ≥98% (SDS-PAGE)
Endotoxin Content <0.06EU/μg protein (LAL test; Lonza).
Reconstitution Reconstitute in 50µl sterile water.
Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

NCBI reference AAH30975.1: IL-33R (human)

Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.