IL-33R (human):Fc (human) (rec.)
|Synonyms||Interleukin-33 Receptor; IL1RL1; DER4; ST2|
The extracellular domain of human IL-33R [ST2] (aa 19-328) is fused to the N-terminus of the Fc region of human IgG1.
Measured by its ability to bind recombinant human IL-33 in a functional ELISA.
|Endotoxin Content||<0.06EU/μg protein (LAL test; Lonza).|
Reconstitute in 50µl sterile water.
Add 1X PBS to the desired protein concentration.
|Formulation||Lyophilized from 0.2μm-filtered solution in PBS.|
|Protein Negative Control|
|Other Product Data||
NCBI reference AAH30975.1: IL-33R (human)
|Declaration||Manufactured by Chimerigen.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
|Product Specification Sheet|
Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.