IraZolve-Mito

CHF 465.00
In stock
REZ-1101024-11 VialCHF 465.00
More Information
Product Details
Product Type Chemical
Properties
Formula

C36H26IrN8 . F6P

MW 762.9 . 145.0
CAS 2172800-69-8
Appearance Solid.
Solubility Soluble in DMSO.
Reconstitution Add 55µL of DMSO to obtain a 10mM stock solution. For working solution see protocol.
Declaration Manufactured by ReZolve Scientific.
Other Product Data

Click here for Original Manufacturer Product Data
Our product description may differ slightly from the original manufacturers product datasheet. For more information on applications please download the Preparation & Staining Protocol. The Expiry Date on the labels is based on storage at Room Temperature only.

InChi Key DIXXBBKSUFVQMR-UHFFFAOYSA-M
Smiles FP(F)(F)(F)F.CN1N=C2[N]([Ir]([N]3=C4C=CC=C3)([N]5=C6C=CC=C5)(C7=CC=CC=C76)(C8=CC=CC=C84)[N]9=CC(C%10=CC=C(C#N)C=C%10)=CC=C92)=N1.[F-]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 6 months after receipt when stored at +4°C.
Stable for at least 2 years after receipt when stored at -20°C.
Documents
Protocols Download PDF
Application Note Download PDF
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

The mitochondrial marker IraZolve-Mito™ is a specialized live cell imaging agent with rapid cell uptake for mitochondria. IraZolve-Mito™ can be used for effective staining and rapid imaging of mitochondria in live and fixed tissues.

IraZolve-Mito™ localizes to mitochondria in live cells and tissue. It is also suitable for the detection of mitochondria in fixed and frozen tissue samples. This cell permeable stain allows mitochondrial detection in tissue samples in one step with no requirement for tissue permeabilization or even sectioning. This agent is suitable for a range of fluorescence applications including imaging by confocal microscopy and multi photon microscopy. Cell penetration and localization of IraZolve-Mito™ has been confirmed in prostate cells, cardiomyocytes and cancer cell lines. Mitochondrial localization has been shown in live tissues, including live adipose tissue and muscle tissue and in paraformaldehyde and cryo-fixed sheep skeletal muscle, cardiac muscle and adipose tissue.

Key Attributes:


  • Simple and quick application

  • Suitable for live cell imaging

  • Suitable for live and fixed tissues

  • Low cytotoxicity

  • Highly resistant to photobleaching

  • Large stoke shift (Ex/Em 405nm / 600nm)

  • Compatible with other fluorescent dyes

  • Ideal for epi-fluorescence, confocal and multiphoton imaging

  • Stable at 4°C

Product References
  1. Investigating Intracellular Localisation and Cytotoxicity Trends for Neutral and Cationic Iridium Tetrazolato Complexes in Live Cells: C. Caporale, et al.; Chemistry 23, 15666 (2017)
  2. Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex: A. Sorvina, et al.; Sci. Rep. 8, 8191 (2018)
© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.