ReZolve Scientific - Superior Cell Imaging Reagents


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ReZolve Scientific - Superior Cell Imaging Reagents    

ReZolve Scientific was established in 2015, as a collaboration between the University of South Australia and Curtin University in Western Australia. The privately owned entity specializes in developing, manufacturing and marketing photostable cell imaging agents. Generating new knowledge by defining the mechanisms of disease and capturing important cellular processes are vital in cell- and microbiology.  The photostability, low cytotoxicity and fast cellular uptake of ReZolve Scientific's fluorophores allow imaging of energy storage, cell signalling, metabolic processes and membrane dynamics in real time. The ReZolve Scientific team is your partner to solve your imaging challenges. 

The proprietary ReZolve™ and IraZolve™ dyes are derived from low-spin transition metal complexes (e.g., Re(I) tricarbonyl tetrazolo complexes and cyclometalated Ir(III) complexes). Emission from the low-spin metal ion complex results from charge transfer between the metal center and highly conjugated ligands. The charge transfer between metal and ligand produces long-lasting fluorescent emission. These complexes are also color-tunable in that the emission of the charge transfer can be altered by incorporation of electron-withdrawing and electron-donating substituents within the metal-bound ligands that modulate the energy gap between the highest occupied and lowest unoccupied molecular orbitals.

AdipoGen Life Sciences provides the complete ReZolve Scientific product range. The products are available from stock. Please contact us if you request further information.

For Product Inquiries: info@adipogen.com


NEW Photostable Fluorescent Cell Imaging Reagents for Live and Fixed Samples

 

ReZolve-ER VisualizationReZolve Scientific provides unique imaging solutions which will reduce your preparation time and extend your imaging time. These unique metal ion complex dyes exhibit high quantum yields, long-lived (millisecond) visible emission, are resistant to photobleaching, and have been developed to allow for live cell imaging. The clear advantage of this technology over small fluorescent molecules or fluorescently labelled antibodies is that it overcomes the limitations of photobleaching, short (nanosecond) emissive lifetime, and the need for cell fixation.


Key Attributes/Advantages:

• Quick and simple to use
• Compatible with live and fixed samples
• Compatible with other dyes
• Can be used for real time localization
• Highly photostable, for longer imaging time
• Stable at room temperature
• Compatible with fluorescence and multiphoton microscopy
• Detectable by X Ray Fluorescence, Raman or Infrared spectroscopy




Dyes Overview

Imaging Dyes Overview

Download also Application Recommendations Overview


Lipid Staining Dyes



ReZolve-L1™

Lipid StainingReZolve-L1™ is a cell-permeant stain which has an affinity for polar lipids and can be used in a wide variety of live and fixed cells. This stain is an effective monitoring and tracer tool of cellular lipid content (e.g. cholesterol, sphingolipid and phospholipid) and intracellular lipid localization and can be used to label lipid droplets and other high lipid-content compartments.

Product Name PID Excitation/Emission (nm)
ReZolve-L1™ REZ-1101021 405 / 550nm
Datasheet and Application Protocol
Product Flyer


IraZolve-L1™

Lipid Staining IraZolveIraZolve-L1™ is a cell-permeant stain that localizes with polar lipids and can be used in a wide variety of live and fixed cells. IraZolve-L1™ provides excellent and rapid lipid staining, labels intracellular lipid droplets and the endoplasmic reticulum in cultured cells. It is perfect to visualize lipid-rich compartments. Similar to ReZolve-L1™, the red emitting IraZolve-L1™ has an affinity for lipids which allows you to monitor changes in cellular lipid localized with lipid droplets and the endoplasmic reticulum.


Product Name PID Excitation/Emission (nm)
IraZolve-L1™ REZ-1101023 405 / 600nm
Datasheet and Application Protocol
Product Flyer


Endoplasmatic Reticulum Staining Dyes



ReZolve-ER™

ER Staining - ReZolve-ERReZolve-ER™ is a live cell imaging agent with rapid cell uptake for imaging the endoplasmic reticulum (ER) in a wide variety of live and fixed cells. This fluorophore is ideal for intermittent or long term monitoring of the endoplasmic reticulum with quick cellular uptake and localization, low cytotoxicity and high photostability to increase image acquisition time.

Product Name PID Excitation/Emission (nm)
ReZolve-ER™ REZ-1101022 405 / 570nm
Datasheet and Application Protocol
Product Flyer


IraZolve-ER Blue™

ER Staining - IraZolve-ER BlueIraZolve-ER Blue™ localizes to the endoplasmic reticulum (ER) in live and fixed cells. It is highly cell-permeable, producing quick and reliable cell staining. This stain has low cytotoxicity and great photostability, making it ideal for time resolved imaging. IraZolve-ER Blue™ is suited to fixed cell applications, including for use with antibody staining, allowing the detailed visualization of the endoplasmic reticular structure in relation to your protein of interest.

Product Name PID Excitation/Emission (nm)
IraZolve-ER Blue™ REZ-1101026 405 / 515nm
Datasheet and Application Protocol
Product Flyer


Mitochondrial Staining Dye



Mitochondrial Staining - IraZolve-MitoIraZolve-Mito™

The mitochondrial marker IraZolve-Mito™ is a specialized live cell imaging agent with rapid cell uptake for mitochondria. IraZolve-Mito™ can be used for effective staining and rapid imaging of mitochondria in live and fixed tissues. This cell permeable stain allows mitochondrial detection in tissue samples in one step with no requirement for tissue permeabilization or even sectioning.

Product Name PID Excitation/Emission (nm)
IraZolve-Mito™ REZ-1101024 405 / 600nm
Datasheet and Application Protocol
Product Flyer


Unique Fluorescent Tag



ReZolve-Alkyne™

Staining with ReZolve-Alkyne labeled ReagentReZolve-Alkyne™ is a cell permeable luminescent alkyne probe which is ideal for conjugation to a range of targets by copper facilitated 'click' reactions. This luminescent tag offers a large Stokes shift (Ex/Em 405/570nm) ideal for fluorescent detection by both microscopy or flow cytometry. This product is also suited to multiphoton microscopy. ReZolve-Alkyne™ tags are highly resistant to photobleaching, allowing more time for image acquisition.

Product Name PID Excitation/Emission (nm)
ReZolve-Alkyne™ REZ-1101025 405 / 570nm
Datasheet and Application Protocol
Product Flyer


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