Tofacitinib

CHF 60.00
In stock
SYN-1032-M0011 mgCHF 60.00
SYN-1032-M0055 mgCHF 84.00
SYN-1032-M01010 mgCHF 108.00
SYN-1032-M05050 mgCHF 287.00
SYN-1032-M100100 mgCHF 407.00
 
More Information
Product Details
Synonyms CP-690550; Xeljanz
Product Type Chemical
Properties
Formula C16H20N6O
MW 312.4
CAS 477600-75-2
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: JAK2 | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key UJLAWZDWDVHWOW-YPMHNXCESA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Tofacitinib is an inhibitor of JAK3 with an IC(50) of 1 nM. It shows up to 100-fold less potency against JAK2 and JAK1.
Product References
  1. Combined use of the JAK3 inhibitor CP-690,550 with mycophenolate mofetil to prevent kidney allograft rejection in nonhuman primates: D.C. Borie, et al.; Transplantation 80, 1756 (2005)
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