Pazopanib hydrochloride

CHF 60.00
In stock
SYN-1058A-M0011 mgCHF 60.00
SYN-1058A-M0055 mgCHF 72.00
SYN-1058A-M01010 mgCHF 84.00
SYN-1058A-M05050 mgCHF 180.00
SYN-1058A-M100100 mgCHF 251.00
 
More Information
Product Details
Synonyms GW-786034; Votrient; Armala
Product Type Chemical
Properties
Formula C21H23N7O2S . HCl
MW 437.5 . 36.5
CAS 635702-64-6
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PDGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key MQHIQUBXFFAOMK-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Pazopanib hydrochloride (GW786034, Votrient, Armala) is a novel, multitargeted inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, FGFR, c-Kit and c-fms with IC(50) values of 10nM, 30nM, 47nM, 84nM, 74nM, 140nM and 146nM, respectively.
Product References
  1. Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity: R. Kumar, et al.; Mol. Cancer Ther. 6, 2012 (2007)
© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.