CHF 60.00
In stock
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Product Details
Synonyms SU6668
Product Type Chemical
Formula C18H18N2O3
MW 310.4
CAS 252916-29-3
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: FGFR - PDGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
SU-6668 is a potent ATP-competitive PDGFR, VEGF and FGFR inhibitor. It has a Ki of 8nM against PDGFR. It is an anti-angiogenic and anti-tumor agent that induces regression of established tumors.
Product References
  1. Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases: L. Sun, et al.; J. Med. Chem. 42, 5120 (1999)
  2. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors: A.D. Laird, et al.; Cancer Res. 60, 4152 (2000)
  3. TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche: M. Yamamoto, et al.; Cancer Res. 68, 9754 (2008)
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