Intedanib

CHF 96.00
In stock
SYN-1091-M0011 mgCHF 96.00
SYN-1091-M0055 mgCHF 144.00
SYN-1091-M01010 mgCHF 227.00
SYN-1091-M05050 mgCHF 778.00
SYN-1091-M100100 mgCHF 1'383.00
 
More Information
Product Details
Synonyms Intedanib; BIBF 1120; Vargatef
Product Type Chemical
Properties
Formula C31H33N5O4
MW 539.6
CAS 656247-17-5
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: FGFR - PDGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key XZXHXSATPCNXJR-ZIADKAODSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Intedanib is an indolinone derivative that potently inhibits VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC(50) values of 34, 13, 13, 69, 37, 108, 59 and 65nM.
Product References
  1. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy: F. Hilberg, et al.; Cancer Res. 68, 4774 (2008)
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