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Intedanib
CHF 96.00
In stock
SYN-1091-M0011 mgCHF 96.00
SYN-1091-M0055 mgCHF 144.00
SYN-1091-M01010 mgCHF 227.00
SYN-1091-M05050 mgCHF 778.00
SYN-1091-M100100 mgCHF 1'383.00
| Product Details | |
|---|---|
| Synonyms | Intedanib; BIBF 1120; Vargatef |
| Product Type | Chemical |
| Properties | |
| Formula | C31H33N5O4 |
| MW | 539.6 |
| CAS | 656247-17-5 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: FGFR - PDGFR | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | XZXHXSATPCNXJR-ZIADKAODSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Intedanib is an indolinone derivative that potently inhibits VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC(50) values of 34, 13, 13, 69, 37, 108, 59 and 65nM.
Product References
- BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy: F. Hilberg, et al.; Cancer Res. 68, 4774 (2008)
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