A-674563 hydrochloride

CHF 209.00
In stock
SYN-1110-M0011 mgCHF 209.00
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Product Details
Synonyms A674563
Product Type Chemical
Formula C22H22N4O . HCl
MW 358.4 . 36.5
CAS 552325-73-2 (free acid)
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: AKT - PKA - CDK7 - CDK5 - CDK4 - CDK2 | Kinase Group: AGC | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
A-674563 is a potent, orally available Akt1 inhibitor with an IC(50) of 11nM. It also displays activity against PKA and CDK2 with IC(50) values of 16 and 46nM respectively.
Product References
  1. Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity: N. Rhodes, et al.; Cancer Res. 68, 2366 (2008)
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