Mubritinib

CHF 60.00
In stock
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More Information
Product Details
Synonyms TAK-165
Product Type Chemical
Properties
Formula C25H23F3N4O2
MW 468.5
CAS 366017-09-6
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: HER2 | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key ZTFBIUXIQYRUNT-MDWZMJQESA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Mubritinib is a potent, irreversible human epithelial growth factor receptor 2 (ErbB2/HER2) inhibitor (IC(50) of 6nM) which displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src kinases.
Product References
  1. Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer: S.S. Sridhar, et al.; Lancet Oncol. 4, 397 (2003)
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