Cabozantinib

CHF 78.00
In stock
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More Information
Product Details
Synonyms XL184; BMS-907351
Product Type Chemical
Properties
Formula C28H24FN3O5
MW 501.5
CAS 849217-68-1
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PDGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key ONIQOQHATWINJY-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Cabozantinib is very potent inhibitor, with an IC(50) of less than 10nM for VEGFR2, MET, Kit and FLT3-ITD.
Product References
  1. Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer: R. Kurzrock, et al.; J. Clin. Oncol. 29, 2660 (2011)
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