Crizotinib

CHF 72.00
In stock
SYN-1139-M0011 mgCHF 72.00
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SYN-1139-M100100 mgCHF 988.00
 
More Information
Product Details
Synonyms PF-02341066
Product Type Chemical
Properties
Formula C21H22Cl2FN5O
MW 450.3
CAS 877399-52-5
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: MEK1 - MEK2 - MKK3&6 - MKK4&7 - MEK - MEK5 | Kinase Group: STE | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key KTEIFNKAUNYNJU-GFCCVEGCSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Crizotinib is a potent inhibitor of c-Met and ALK with IC(50) of 11nM and 24nM, respectively.
Product References
  1. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma: J.G. Christensen, et al.; Mol. Cancer Ther. 6, 3314 (2007)
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