SYN-1139-M0055 mgCHF 132.00
|Solubility||Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: MEK1 - MEK2 - MKK3&6 - MKK4&7 - MEK - MEK5 | Kinase Group: STE | Substrate: Serine-Threonine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Crizotinib is a potent inhibitor of c-Met and ALK with IC(50) of 11nM and 24nM, respectively.
- Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma: J.G. Christensen, et al.; Mol. Cancer Ther. 6, 3314 (2007)