SYN-1154-M0011 mgCHF 227.00
SYN-1154-M0055 mgCHF 461.00
SYN-1154-M01010 mgCHF 724.00
|Solubility||Soluble in DMSO or ethanol.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: CSF1R, FLT3 | Kinase Group: CMGC | Substrate: Tyrosine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
JNJ-28312141 is an orally active tyrosine kinase inhibitor for FMS with an IC(50) of 0.69nM and a cell assay IC(50) of 2.6nM. It is an active CSF1R inhibitor (Colony-stimulating factor-1 receptor) and also a FLT3 inhibitor.
- JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia: C.L. Manthey, et al.; Mol. Cancer Ther. 8, 3151 (2009)