JNJ-28312141

CHF 227.00
In stock
SYN-1154-M0011 mgCHF 227.00
SYN-1154-M0055 mgCHF 461.00
SYN-1154-M01010 mgCHF 724.00
SYN-1154-M05050 mgCHF 2'436.00
SYN-1154-M100100 mgCHF 3'884.00
 
More Information
Product Details
Synonyms JNJ28312141
Product Type Chemical
Properties
Formula C26H32N6O2
MW 460.6
CAS 885692-52-4
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: CSF1R, FLT3 | Kinase Group: CMGC | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key GUBJNPWVIUFSTR-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
JNJ-28312141 is an orally active tyrosine kinase inhibitor for FMS with an IC(50) of 0.69nM and a cell assay IC(50) of 2.6nM. It is an active CSF1R inhibitor (Colony-stimulating factor-1 receptor) and also a FLT3 inhibitor.
Product References
  1. JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia: C.L. Manthey, et al.; Mol. Cancer Ther. 8, 3151 (2009)
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