Ruboxistaurin hydrochloride

CHF 198.00
In stock
SYN-1172-M0011 mgCHF 198.00
SYN-1172-M0055 mgCHF 329.00
SYN-1172-M01010 mgCHF 515.00
SYN-1172-M05050 mgCHF 1'568.00
SYN-1172-M100100 mgCHF 2'490.00
 
More Information
Product Details
Synonyms LY333531
Product Type Chemical
Properties
Formula C28H28N4O3 . HCl
MW 468.5 . 36.5
CAS 169939-93-9
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: PKC | Kinase Group: AGC | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key NYQIEYDJYFVLPO-FERBBOLQSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
LY333531 is a potent, selective inhibitor of Protein Kinase C isozymes, PKCβI (IC(50) of 4.7nM) and PKCβII (IC(50) of 5.9nM).
Product References
  1. (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta: M.R. Jirousek, et al.; J. Med. Chem. 39, 2664 (1996)
  2. Effects of protein kinase C inhibitors on thromboxane production by thrombin-stimulated platelets: G.P. Samokhin, et al.; Eur. J. Pharmacol. 386, 297 (1999)
  3. Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCbeta: M.M. Faul, et al.; Bioorg. Med. Chem. Lett. 13, 1857 (2003)
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