Rapamycin

CHF 60.00
In stock
SYN-1185-M0011 mgCHF 60.00
SYN-1185-M0055 mgCHF 84.00
SYN-1185-M01010 mgCHF 120.00
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Product Details
Synonyms Sirolimus; AY-22989; WY-090217
Product Type Chemical
Properties
Formula C51H79NO13
MW 914.2
CAS 53123-88-9
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: mTOR | Kinase Group: Atypical (PIKK) | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key QFJCIRLUMZQUOT-HPLJOQBZSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Rapamycin is a specific mTOR inhibitor with an IC(50) of ~0.1nM.

Product References
  1. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase: C.J. Kuo, et al.; Nature 358, 70 (1992)
  2. Rapamycins: mechanism of action and cellular resistance: S. Huang, et al.; Cancer Biol. Ther. 2, 222 (2003)
  3. Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis: S. Kobayashi, et al.; Cancer Sci. 98, 726 (2007)
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