CHF 108.00
In stock
SYN-1210-M0011 mgCHF 108.00
SYN-1210-M0055 mgCHF 263.00
SYN-1210-M01010 mgCHF 419.00
SYN-1210-M05050 mgCHF 1'077.00
SYN-1210-M100100 mgCHF 1'796.00
More Information
Product Details
Synonyms AST487
Product Type Chemical
Formula C26H30F3N7O2
MW 529.6
CAS 630124-46-8
Purity Chemicals ≥95%
Appearance Solid.
Solubility Slightly soluble (< 1mg/mL) in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: Flt3 | Kinase Group: TK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML.

Product References
  1. Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells: E. Weisberg, et al.; Blood 112, 5161 (2008)
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