Voriconazole

CHF 60.00
In stock
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Product Details
Synonyms VFEND-UK-109-496
Product Type Chemical
Properties
Formula C16H14F3N5O
MW 349.3
CAS 137234-62-9
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: N/A | Kinase Group: Pfizer Licensed | Substrate: N/A

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InChi Key BCEHBSKCWLPMDN-MGPLVRAMSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF
Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. Voriconzole shows anti-Candida albicans activity at 0.007-8 micrograms/mL is assays. Voriconzole is a potent cytochrome P450 inhibitor with IC50's in the low to mid micromolar range. Voriconazole shows potent antitrypanosomal activity (IC50=95.6nM) against amastigote stage of Trypanosoma cruzi infected in mouse NIH/3T3 cells.
Product References
  1. Antifungal activity of the new azole UK-109 496 (voriconazole): addition and clarification: R. Kappe, et al.; Mycoses 44, 432 (2001)
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