CHF 60.00
In stock
SYN-3014-M0011 mgCHF 60.00
SYN-3014-M0055 mgCHF 78.00
SYN-3014-M01010 mgCHF 90.00
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Product Details
Synonyms UK-383,367
Product Type Chemical
Formula C15H24N4O4
MW 324.4
CAS 348622-88-8
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: BMP-1 | Kinase Group: N/A | Substrate: N/A

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

UK 383367 is a potent and selective inhibitor of BMP-1 (procollagen C-proteinase; PCP) with an IC(50) of 44nM. It is selective for BMP-1 over MMPs 1, 2, 3, 9 and 14 with IC(50) values are >10,000nM for listed MMPs.

Product References
  1. Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity: G.A. Allan, et al.; Xenobiotica 36, 399 (2006)
  2. Potent and selective nonpeptidic inhibitors of procollagen C-proteinase: P.V. Fish, et al.; J. Med. Chem. 50, 3442 (2007)
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