Linezolid

CHF 60.00
In stock
SYN-3021-M0011 mgCHF 60.00
SYN-3021-M0055 mgCHF 78.00
SYN-3021-M01010 mgCHF 90.00
SYN-3021-M05050 mgCHF 329.00
SYN-3021-M100100 mgCHF 515.00
 
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Product Details
Synonyms Zyvox
Product Type Chemical
Properties
Formula C16H20FN3O4
MW 337.4
CAS 165800-03-3
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: Ribosome (23S) | Kinase Group: N/A | Substrate: N/A

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key TYZROVQLWOKYKF-ZDUSSCGKSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Linezolid displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo, including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). Linezolid has shown excellent efficacy against gram-positive cocci, including Staphylococcus aureus, coagulase-negative staphylococci, enterococci, and streptococci, with MICs ranging from 0.5 to 4µg/ml. Linezolid is a potent inhibitor of cell-free transcription-translation in E. coli, exhibiting 50% inhibitory concentrations (IC50s) of 1.8µM. The drug works by inhibiting the initiation of bacterial protein synthesis and has excellent bioavailability in animal studies.
Product References
  1. Vancomycin versus linezolid in the treatment of methicillin-resistant Staphylococcus aureus meningitis: O.R. Sipahi, et al.; Surg. Infect. (Larchmt) 14, 357 (2013)
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