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Tubastatin A . HCl
CHF 60.00
In stock
SYN-3042-M0011 mgCHF 60.00
SYN-3042-M0055 mgCHF 108.00
SYN-3042-M01010 mgCHF 156.00
SYN-3042-M05050 mgCHF 467.00
SYN-3042-M100100 mgCHF 706.00
| Product Details | |
|---|---|
| Synonyms | N-Hydroxy-4-((2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride |
| Product Type | Chemical |
| Properties | |
| Formula | C20H21N3O2 . HCl |
| MW | 335.4 . 36.5 |
| CAS | 1310693-92-5 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: HDAC6 | Kinase Group: N/A | Substrate: N/A Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | LJTSJTWIMOGKRJ-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 4nM. It has a 100 to 1000-fold selectivity for HDAC6 over other HDAC classes.
Product References
- HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease: C. d'Ydewalle, et al.; Nat. Med. 17, 968 (2011)
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