Peroxiredoxin 3 (Prdx3) (human) ELISA Kit (10x96T)

CHF 5'021.00
In stock
YIF-LF-EK011510 x 96 wellsCHF 5'021.00
More Information
Product Details
Synonyms AOP1; PRDX3; AOP-1; HBC189; Prx-III; EC=1.11.1.15; Peroxiredoxin-3; Peroxiredoxin III; Protein MER5 Homolog; Antioxidant Protein 1; Thioredoxin-dependent Peroxide Reductase, Mitochondrial
Product Type Kit
Properties
Application Set Compound Screening
Crossreactivity Human
Quantity

10x96 wells

Sensitivity 2 ng/ml
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx 6 belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx 1, 2, and 6 in cytosol, Prx 3 in mitochondria, Prx 4 in ER and secretion, Prx 5 showing complicated distribution including peroxisome, mitochondria and cytosol (1). Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling.

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