α-Enolase (ENO1 Non Neuronal Enolase) (human) ELISA Kit

CHF 628.00
In stock
YIF-LF-EK02001 x 96 wellsCHF 628.00
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Product Details
Synonyms NNE; ENO1; MPB-1; MBP-1; ENO1L1; Enolase 1; EC=4.2.1.11; α-Enolase; Non-Neural Enolase; Phosphopyruvate Hydratase; Plasminogen-binding Protein; C-myc Promoter-binding Protein; 2-Phospho-D-Glycerate Hydro-lyase
Product Type Kit
Properties
Application Set Compound Screening
Crossreactivity Human
Quantity

1x96 wells

Sensitivity 0.218 ng/ml
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate. It comprises three distinct subunits, α, β and γ. Non Neuronal Enolase(ENO1) is an isoform of mammalian enolase and is composed of 2 α subunits. The gene for ENO1 also encodes a shorter monomeric structural lens protein, tau-crystallin. Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Used as a diagnostic marker for many tumors and, in the heterodimeric form, α/γ, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against α-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.

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