Cymax IL-4 (human) ELISA Kit

Specifications / Handling

More Information
Product Details
Synonyms	IL4; IL-4; BSF-1; Pitrakinra; Binetrakin; Interleukin-4; B-Cell Stimulatory Factor 1; Lymphocyte Stimulatory Factor 1
Product Type	Kit
Properties
Application Set	Compound Screening
Crossreactivity	Human
Quantity	1x96 wells
Sensitivity	0.3757 pg/ml
Range	1.56 pg/ml - 100 pg/ml
Sample Type	Buffers Cell Culture Supernatant Cell Lysate Plasma Serum
Assay Type	Sandwich
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by AbFrontier
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Any unused reconstituted standard should be discarded or frozen at -80℃. Standard can be frozen and thawed one time only without loss of immunoreactivity.
Documents
Manual	Download PDF
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Description

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-γ, and lymphotoxin (TNF-β). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.

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