Cymax IL-6 (human) ELISA Kit

CHF 390.00
In stock
YIF-LF-EK02601 x 96 wellsCHF 390.00
More Information
Product Details
Synonyms IL6; CDF; IL-6; BSF-2; IFNB2; IFN-β-2; Interleukin-6; Interferon β-2; Hybridoma Growth Factor; CTL Differentiation Factor; B-Cell Stimulatory Factor 2
Product Type Kit
Properties
Application Set Compound Screening
Crossreactivity Human
Quantity

1x96 wells

Sensitivity 1.160 pg/ml
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Interleukin-6 (IL-6) is a pleiotropic α-helical cytokine that plays important roles in a central player in the regulation of inflammation, haematopoiesis, immune response and host defense mechanisms. Human IL-6 molecular weight ranges between 21 and 28 kDa, depending on the state of glycosylation and phosphorylation. Mature human IL-6 is 183 amino acids and shares the homology between human and rat IL-6 is 41% at the amino acid level. IL-6 interacts with its receptor complex consisting of the membrane-bound IL-6 receptor (IL-6R) and the signal transducing protein gp130. IL-6R can exist as a soluble protein (sIL-6R), which binds the ligand IL-6. This soluble complex can bind to gp130 on cells that lack the membrane-bound IL-6R and initiate signaling. Two major signalling pathways are activated by IL-6, the JAK/STAT pathway and MAPK cascade.

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