Cymax TRAIL (human) ELISA Kit

CHF 450.00
In stock
YIF-LF-EK02661 x 96 wellsCHF 450.00
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Product Details
Synonyms CD253; APO2L; Apo-2L; TNFSF10; Apo-2 Ligand; Protein TRAIL; TNF-related Apoptosis-inducing Ligand; Tumor Necrosis Factor Ligand Superfamily Member 10
Product Type Kit
Application Set Compound Screening
Crossreactivity Human

1x96 wells

Sensitivity 0.065 pg/ml
Range 31.25 pg/ml - 1500 pg/ml
Sample Type Buffers
Cell Culture Supernatant
Cell Lysate
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Manual Download PDF
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Product Specification Sheet
Datasheet Download PDF

TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to fi ve distinct receptors: TRAIL-R1 (DR4; Apo2;CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A; TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1;LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2;TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerized TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducingthe formation of the so-called multiprotein death-inducing signaling complex (DISC).

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