Cymax IL-1α (human) ELISA Kit

CHF 450.00
In stock
YIF-LF-EK02901 x 96 wellsCHF 450.00
More Information
Product Details
Synonyms Il1a; IL-1 α; Interleukin-1 α
Product Type Kit
Application Set Compound Screening
Crossreactivity Human

1x96 wells

Sensitivity 0.521 pg/ml
Range 3.91 pg/ml - 250 pg/ml
Sample Type Buffers
Cell Culture Supernatant
Cell Lysate
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1α and IL-1β. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1α was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1α upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1α is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1α and IL-1β. Although most activators fully rely on the inflammasome for IL-1α secretion, some induce the processing and secretion of IL-1α in an inflammasome-independent manner.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.