Cymax IL-17 (mouse) ELISA Kit

CHF 390.00
In stock
YIF-LF-EK03031 x 96 wellsCHF 390.00
More Information
Product Details
Synonyms IL17; IL-17; Interleukin-17
Product Type Kit
Properties
Application Set Quantitative ELISA
Crossreactivity Mouse
Quantity

1x96 wells

Sensitivity 3.573 pg/ml
Range 10.9 pg/ml - 700 pg/ml
Sample Type Buffers
Cell Culture Supernatant
Cell Lysate
Plasma
Serum
Assay Type Sandwich
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Any unused reconstituted standard should be discarded or frozen at -80℃.
Standard can be frozen and thawed one time only without loss of immunoreactivity.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation. IL-17 is produced by T-helper cells and is induced by IL–23 which results in destructive tissue damage in delayed-type reactions. IL-17 is a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen’s cellular matrix. IL-17 acts synergistically with tumor necrosis factor and interleukin-1. Numerous immune regulatory functions have been reported for the IL-17 family of cytokines, presumably due to their induction of many immune signaling molecules. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with allergic responses. IL-17 induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α, and MCP-1) and prostaglandins from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes, and macrophages). The IL-17 family has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently psoriasis.

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