anti-c-Myc, mAb (LF10E3)

CHF 322.00
In stock
YIF-LF-MA0046100 µlCHF 322.00
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Product Details
Synonyms MYC; bHLHe39; BHLHE39; Proto-Oncogene c-Myc; Transcription Factor p64; Myc Proto-Oncogene Protein; Class E Basic Helix-Loop-Helix Protein 39; Epitope Tag
Product Type Monoclonal Antibody
Properties
Clone LF10E3
Isotype Mouse IgG1 κ
Immunogen/Antigen Synthetic peptide.
Application

Western Blot (1:2,000)
Immunoprecipitation (1~2 μg/ml lysates)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Epitope tags can be used to label and detect proteins with immunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged proteina's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast, insect and mammalian cell systems. Myc proteins are nuclear proteins with relatively short half-lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas. Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

Product References

1) Evan, G.I. et al. (1985) Mol. Cell. Biol. 5: 3610-3616. (General)
2) Munro, S. and Pelham, H.R. (1984) EMBO J.3: 3087-3093. (General)
3) Alitalo, K. et al. (1983) Proc. Natl. Acad. Sci.USA 80: 1707-1711. (General)

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