anti-Selenoprotein M, mAb (4C2)

CHF 322.00
In stock
YIF-LF-MA0057100 µlCHF 322.00
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Product Details
Synonyms SEPM; SelM; SELM; Selenoprotein M
Product Type Monoclonal Antibody
Properties
Clone 4C2
Isotype Mouse IgG1 κ
Immunogen/Antigen Recombinant human protein purified from E. coli.
Application

ELISA
Western Blot (1:2,000)
Immunoprecipitation (1~2 μl)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in anti-oxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/ disulfide exchange. Selenoprotein M(SelM) is especially expressed in a mammalian brain and is localized to the perinuclear structures (Golgi/ER). The roles of selM have not been clearly identified until present time. May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation

Product References

1) Korotkov, K.V. et al (2002) Mol.Cell.Biol. 22(5) 1402-1411. (General)
2) Chen, J. and Berry M.J. (2003) J.Neurochem. 86, 1-12. (General)
3) Ganther, H.E. (1999) Carcinogenesis 20(9) 1657-1666. (General)

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