anti-α-Tubulin, mAb (4G1)

CHF 322.00
In stock
YIF-LF-MA0117100 µlCHF 322.00
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Product Details
Synonyms TUBA3; TUBA1A; α-Tubulin 3; Tubulin B-α-1; Tubulin α-3 Chain; Tubulin α-1A Chain
Product Type Monoclonal Antibody
Properties
Clone 4G1
Isotype Mouse IgG1 κ
Immunogen/Antigen Synthetic peptide (KLH coupled) corresponding to C-terminal residues of human tubulin.
Application

Western Blot (1:2,000~10,000)
IHC-P

Crossreactivity Human
Mouse
Rat
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Tubulin is a heterodimer consisting of α and β-tubulin subunits. It is nearly ubiquitous among eukaryotic cells. The α and β tubulins, which are each about 55 kDa MW, are homologous but not identical. α-β tubulin heterodimer is the basic building block of microtubules. This intracellular cylindrical filamentous structure is present in almost eukaryotic cells. microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α-chain.

Product References

1) Blose SH, et. al. Journal of Cell Biology (1984), 98(3):847-58. (General)
2) Breitling F, et. al. Journal of Molecular Biology (1986) 189(2):367-70. (General)
3) Biochim Biophys Acta (1989), 1012(1):46-56. (General)
4) Biochemistry (1993) 32(18):4955-61. (General)

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