anti-APOA1, mAb (2G4)

CHF 322.00
In stock
YIF-LF-MA0127100 µlCHF 322.00
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Product Details
Synonyms Apolipoprotein A1
Product Type Monoclonal Antibody
Properties
Clone 2G4
Isotype Mouse IgG1 κ
Immunogen/Antigen Purified human Apolipoprotein A-I protein.
Application

ELISA
Western Blot (1:2,000)
IHC-P

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Apolipoprotien A-I (Apo A-I) is one of the major protein components in high density lipoprotein (HDL). The molecular weight is reported to be 28.3 kDa. Apo A-I acts as a cofactor for lecithin cholesterol acyl transferase (LCAT), which is important in removing excess cholesterol from tissues and incorporating it into HDL for reverse transport to the liver. Some of the apolipoproteins act as ligands to tissue receptors, while others activate or inhibit enzymes involved in metabolic steps in the circulation or tissues. Apo A-I plays important roles in atherosclerosis, tangier disease, coronary heart disease. Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Product References

1) G. Walldius et al. (2004) Journal of Internal Medicine 255: 188-205. (General)
2) Yves L. Marcel et al. (2003) Genetics and Molecular Biology 14:151-157. (General)

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