anti-Chromogranin A, mAb (23A1)

CHF 315.00
In stock
YIF-LF-MA0140100 µlCHF 315.00
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Product Details
Synonyms CHGA
Product Type Monoclonal Antibody
Clone 23A1
Isotype Mouse IgG2b κ
Immunogen/Antigen Recombinant human CGA protein purified from E. coli.

Western Blot (1:2,000)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Isotype Negative Control

Mouse IgG2b Isotype Control

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

Chromogranin A (CGA) was identified as a major soluble protein in adrenal medullary chromaffin granules. CHGA derived peptides are also known as Catestatin, Vasostatin-I,-II, Prochromacin, Pancreastatin and Parastatin. CGA and its processed products are involved in the biogenesis of densecore secretory granules and have a role in immunity against microbes, and function as potential markers for several types of tumors. They have also been implicated in neurodegenerative disorders and cardiovascular diseases such as a hypertension. CGA accumulates in the senile and preamyloid plaques of Alzheimer’s disease, in Lewy bodies of Parkinson’s disease, and in the swollen neurons of Pick’s disease. Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.

Product References

1) Steinbrenner, H. et al (2006) Free Radic. Biol. Med. 40: 1513-1523. (General)
2) Burk, R.F. et al (2005) Annu. Rev. Nutr. 25: 215-235. (General)

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