anti-IgM (human) (13A11)

CHF 322.00
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YIF-LF-MA0164100 µlCHF 322.00
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Product Details
Synonyms IGHM; Ig μ Chain C Region
Product Type Monoclonal Antibody
Clone 13A11
Isotype Mouse IgG1 λ
Immunogen/Antigen Protein purified from human plasma.
Application ELISA
Western Blot (1:2,000)
Immunoprecipitation (0.5 μl)
Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Product Specification Sheet
Datasheet Download PDF
Immunoglobulin M (IgM) forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer and the J chain is attached to most pentamers. It has a large molecular mass of approximately 900 kD. Due to its polymeric nature, IgM possesses high avidity, and is particularly effective at complement activation. It is sometimes called a "natural antibody", but it is likely that the antibodies arise due to sensitization in the very young to antigens that are naturally occurring in nature. IgM is the first immunoglobulin expressed by mature B cells. IgM antibodies appear early in the course of an infection and usually do not reappear after further exposure. IgM antibodies do not pass across the human placenta. These two biological properties of IgM make it useful in the diagnosis of infectious diseases. Demonstrating IgM antibodies in patients serum indicates recent or in serum from a neonate intrauterine infection such as congenital rubella.
Product References
1) Grubb R. Exp Clin Immunogenet. (1995) vol.12(3): pp.191-7. (General)
2) Stewart AK, Schwartz RS. Blood. (1994) vol.83(7): pp.1717-30. (General)
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