anti-α1-Acid Glycoprotein, mAb (AGP) (27A1)

CHF 315.00
In stock
YIF-LF-MA0167100 µlCHF 315.00
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Product Details
Synonyms AGP1; ORM1; AGP 1; OMD 1; Orosomucoid-1; α-1-Acid Glycoprotein 1
Product Type Monoclonal Antibody
Clone 27A1
Isotype Mouse IgG1 κ
Immunogen/Antigen Protein purified from human plasma.

Western Blot (1:1,000)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Isotype Negative Control

Mouse IgG1 Isotype Control

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

α-1-Acid glycoprotein (AGP) is a protein with a molecular weight of 41~43 kDa and is heavily glycosylated (45%). Due to the presence of sialic acids, it is negatively charged (pI=2.7-3.2). AGP is one of the major acute phase proteins in humans. As most acute phase proteins, its serum concentration increases in response to systemic tissue injury, inflammation or infection, and these changes in serum protein concentrations have been correlated with increases in hepatic synthesis. Also, its glycosylation pattern can change depending on the type of inflammation. The biological function of AGP remains unknown; however, AGP is believed to regulate the interaction between blood cells and endothelial cells, and regulates the extravasation of the cells during infection and inflammation. Inter-α-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Product References

1) Fournier T, et al, Biochim Biophys Acta. (2000) vol.1482(1-2): pp.157-71. (General)
2) Hochepied T, et al, Cytokine Growth Factor Rev. (2003) vol.14(1): pp.25-34. (General)

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