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anti-Ad5 Hexon, mAb (65H6)
Product Details | |
---|---|
Synonyms | L3; CP-H; Protein II; Hexon Protein |
Product Type | Monoclonal Antibody |
Properties | |
Clone | 65H6 |
Isotype | Mouse IgG κ |
Immunogen/Antigen | Ad5 Hexon protein purified from mammalian cell. |
Application |
Western Blot (1:5,000) |
Crossreactivity | Virus |
Purity Detail | Ammonium sulfate precipitation. |
Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by AbFrontier |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet |
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Hexon is a one of adenovirus capsid proteins (240 hexons per particle). Each hexon capsomere is homotrimer of the hexon protein, a complex protein of >900 residues. 49 human adenovirus serotypes have been discovered, and divided into six subgroup, A to E, based on a variety of observation. They are an important cause of respiratory illness, conjunctivitis, and gastroenteritis and have more recently been recognized as a potential cause of sexually transmitted diseases. Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose. More recently, polyclonal antibodies against adenovirus were used for quantifying adenoviral titers. This protein is one of the structural proteins in the viral coat and is synthesized during late infection.
1) Swenson, P. D. et al. (1995) J. Clin. Microbiol. 33:2728-2731. (General)
2) Kozarsky, K. F. et al. (1993) Curr. Opin. Genet. Dev. 3:499-503. (General)
3) O’Carroll, S. J. et al. (2000) Biotechniques. 28:408-412. (General)