anti-α-B Glycoprotein (A1BG), mAb (51A6)
| Product Details | |
|---|---|
| Synonyms | A1BG; α-1B-Glycoprotein; α-1-B Glycoprotein |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 51A6 |
| Isotype | Mouse IgG1 κ |
| Immunogen/Antigen | Protein purified from human plasma. |
| Application |
ELISA |
| Crossreactivity | Human |
| Purity Detail | Ammonium sulfate precipitation. |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
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α-1-B glycoprotein (A1BG) which is a plasma protein with no known function belongs to the immunoglobulin superfamily. Although the human A1BG has been known for four decades, and the information about the amino acid sequence, chromosomal assignment, and even genetic polymorphism in different populations have been known, no biological function has been suggested. A1BG (Mr approximately equal to 63,000) consists of one polypeptide chain of 474 amino acids with four glucosamine oligosaccharides. The polypeptide has five intrachain disulfide bonds and consists of five repeating structural domains, each containing about 95 amino acids and one disulfide bond. Recently human cystein-rich secretory protein 3 (CRISP-3) has been found to be a binding partner of A1BG, suggesting the A1BG-CRISP-3 complex displays a protecting function from a potentially harmful effect of free CRISP-3 in circulation.
1) Udby, L. et al., (2004) Biochemistry 43:12877-12886. (General)
2) Ishioka, N. et al., (1986) Proc Natl Acad Sci U S A. 83:2363-2367. (General)
