anti-β-hCG, mAb (Chorionic Gonadotropin), mAb (7H4)

CHF 322.00
In stock
YIF-LF-MA0269100 µlCHF 322.00
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Product Details
Synonyms CGB; CGB3; CG-β; Choriogonadotropin Subunit β; Chorionic Gonadotrophin Chain β
Product Type Monoclonal Antibody
Properties
Clone 7H4
Isotype Mouse IgG1 κ
Immunogen/Antigen Human chorionic gonadtropin protein.
Application

ELISA
Western Blot (1:2,000)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy. Its role is to prevent the disintegration of the corpus luteum of the ovary, thereby to maintain progesterone production that is critical for a pregnancy. hCG is a heterodimeric glycoprotein hormone of placental origin, composed of 237 amino acids, with a molecular mass of 36.7 kD. hCG consists of noncovalently associated α and β subunits. The peptide moiety of the α subunit is common to the pituitary glycoprotein hormones, luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), whereas the β subunit is specific to each particular hormone. Early pregnancy testing, in general, is based on the detection or measurement of β-hCG. Because β-hCG is produced also by some kinds of tumor including choriocarcinoma, germ cell tumors, teratoma, β-hCG is an important tumor marker. hCG has been identified by immunohistochemical methods in prostate, bladder, testicular, colorectal, ovarian, and other cancers. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Product References

1) Thwaini A et al. (2006) Urol Int. 2006;77(4):289-296 (General)
2) Okamoto T et al. (2001) J Endocrinol. 171(3):435-443. (General)
3) Birken S et al. (1988) Endocrinology. 123(1):572-583. (General)

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