anti-Cyclin D1, mAb (AF2G5)

CHF 322.00
In stock
YIF-LF-MA0325100 µlCHF 322.00
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Product Details
Synonyms BCL1; CCND1; BCL-1; BCL-1 Oncogene; PRAD1 Oncogene; G1/S-specific Cyclin-D1; B-Cell Lymphoma 1 Protein
Product Type Monoclonal Antibody
Properties
Clone AF2G5
Isotype Mouse IgG1 κ
Immunogen/Antigen Recombinant human His-Cyclin D1 protein purified from E. coli.
Application

Western Blot (1:1,000)
Immunoprecipitation (2 μl)

Crossreactivity Human
Rat
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Cyclin D1 (Bcl-1 oncogene product), is a member of the Cyclin family that help control transition between phases of the cell cycle by acting as regulatory subunits of the Cdks. The D-type Cyclins are composed of three subtypes, Cyclin D1, D2 and D3. Cyclin D1 is essential for control of the cell cycle at the G1/S transitions and interacts with Cdk4 or Cdk6 protein kinases. On the recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Also Cyclin D1 involves in development and cancer. Essential for the control of the cell cycle at the G1/S (start) transition.

Product References

1) Toru Motokura et al., (1992) J Biol Chem 267(28):20412-20415. (General)
2) Xiang Zhang et al., (2005) Journal of Clinical Neuroscience 12(2):166-168. (General)
3) Sherr CJ, (1993) Cell 73:1059-1065. (General)
4) Hirofumi Nakagami et al., (2002) The Plant Cell 14:1847-1857. (General)

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