anti-PEZ, mAb (T40-AF7C8)

CHF 322.00
In stock
YIF-LF-MA0338100 µlCHF 322.00
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Product Details
Synonyms PEZ; PTPN14; EC=3.1.3.48; Protein-Tyrosine Phosphatase Pez; Tyrosine-Protein Phosphatase Non-Receptor Type 14
Product Type Monoclonal Antibody
Properties
Clone T40-AF7C8
Isotype Mouse IgG1 κ
Immunogen/Antigen Recombinant human protein purified from E. coli.
Application

Western Blot (1:500)

Crossreactivity Human
Purity Detail Ammonium sulfate precipitation.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Protein-tyrosine phosphatase 14 (PTPN14/PTPD2/PEZ) is a 130kDa multidomain cytosolic protein, and belongs to the NT6 subtype of PTPs. It is characterized by an N-terminal FERM domain (Band 4.1, ezrin, radixin, moesin homology) and a C-terminal PTP domain. Pez(Phosphatase with ezrin domain) may play a role in regulating endothelial cell proliferation during vascular injury and angiogenesis. B-Catenin, a central component of adherens junctions, has been identified as a PTPN14 substrate. TGF, which inhibits cell proliferation but not migration, also inhibits translocation of PTPN14 from the cytosol to the nucleus.

Product References

1) Wadham C et al, (2003) Mol Biol Cell 14(6):2520-9. (General)
2) Smith AL et al., (1995) Biochem Biophys Res Commun 209(3):959-65. (General)
3) Barr AJ et al, (2006) Proteins 63(4):1132-6. (General)

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