anti-N-Myc, mAb (6A4I)

CHF 315.00
In stock
YIF-LF-MA0356100 µlCHF 315.00
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Product Details
Synonyms MYCN; BHLHE37; bHLHe37; N-Nyc Proto-Oncogene Protein; Class E Basic Helix-Loop-Helix Protein 37
Product Type Monoclonal Antibody
Clone 6A4I
Isotype Mouse IgG1 κ
Immunogen/Antigen Synthetic peptide.

Western Blot (1:2,000)

Crossreactivity Human
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Isotype Negative Control

Mouse IgG1 Isotype Control

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

The N-myc gene belongs to a family of proto-oncogenes, including the highly related c-myc, N-myc, and L-myc genes, that encode transcription factors sharing many structural and biochemical functions . The structural motifs conserved between the MYC proteins include a basic helix-loop-helix domain and a leucine zipper domain involved in DNA-protein and protein-protein interactions, respectively. These motifs are also found in numerous transcription factors that control cell determination during diverse cell processes such as myogenesis, neurogenesis, and sex determination. May function as a transcription factor.

Product References

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3) Caudy, M. Et al. (1988) Cell 55:1061-1067. (General)
4) Galderisi, U. Et al. (1999) J.Cell.Biochem. 73:97-105. (General)
5) Malynn, B. Et al. (2000) Genes Dev. 14:1390-1399. (General)
6) Olson, E. N. (1990) Genes Dev. 4:1454-1461. (General)
7) Thisse, B. Et al. (1988) EMBO J. 7:2175-2183. (General)
8) Villares, R. Et al. (1987) Cell 50:415-424. (General)

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