anti-N-Myc, mAb (6A4I)

CHF 322.00
In stock
YIF-LF-MA0356100 µlCHF 322.00
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Product Details
Synonyms MYCN; BHLHE37; bHLHe37; N-Nyc Proto-Oncogene Protein; Class E Basic Helix-Loop-Helix Protein 37
Product Type Monoclonal Antibody
Properties
Clone 6A4I
Isotype Mouse IgG1 κ
Immunogen/Antigen Synthetic peptide.
Application

Western Blot (1:2,000)

Crossreactivity Human
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

The N-myc gene belongs to a family of proto-oncogenes, including the highly related c-myc, N-myc, and L-myc genes, that encode transcription factors sharing many structural and biochemical functions . The structural motifs conserved between the MYC proteins include a basic helix-loop-helix domain and a leucine zipper domain involved in DNA-protein and protein-protein interactions, respectively. These motifs are also found in numerous transcription factors that control cell determination during diverse cell processes such as myogenesis, neurogenesis, and sex determination. May function as a transcription factor.

Product References

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3) Caudy, M. Et al. (1988) Cell 55:1061-1067. (General)
4) Galderisi, U. Et al. (1999) J.Cell.Biochem. 73:97-105. (General)
5) Malynn, B. Et al. (2000) Genes Dev. 14:1390-1399. (General)
6) Olson, E. N. (1990) Genes Dev. 4:1454-1461. (General)
7) Thisse, B. Et al. (1988) EMBO J. 7:2175-2183. (General)
8) Villares, R. Et al. (1987) Cell 50:415-424. (General)

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