Catecholamine-sulfating Phenol Sulfotransferase (human) (rec.)

CHF 366.00
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YIF-LF-P00490.25 mgCHF 366.00
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Product Details
Synonyms STM; HAST3; M-PST; TL-PST; SULT1A3; EC=2.8.2.1; ST1A3/ST1A4; Sulfotransferase 1A3/1A4; Aryl Sulfotransferase 1A3/1A4; Placental Estrogen Sulfotransferase; Thermolabile Phenol Sulfotransferase; Sulfotransferase; Monoamine-preferring
Product Type Protein
Properties
Source/Host E. coli
Crossreactivity Human
Purity ≥95% (SDS-PAGE)
Concentration 1 mg/ml
Formulation Liquid in 20mM HEPES, pH7.0, 10% Glycerol.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping DRY ICE
Short Term Storage -20°C
Long Term Storage -80°C
Handling Advice Avoid freeze/thaw cycles.
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Product Specification Sheet
Datasheet Download PDF

The human Catecholamine-Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyses the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the sulfating activity and expressed in the human intestine, brain, platelet and other tissues. In the brain it may play a role in regulating the levels of dopamine. It also serves as a detoxifying function in the intestine, where it may detoxify potentially lethal dietary monoamines.

Product References

1) Pai, T.G. et al. (2003) J. Biol. Chem. 278, 1525-1532. (General)
2) Pai, T.G. et al. (2002) J. Biol. Chem. 277,43813-43820. (General)
3) Coughtrie, M.W.H. (2002) Pharmacogenomics J. 2, 297-308. (General)

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