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Transthyretin GST (human) (rec.)
Product Details | |
---|---|
Synonyms | TTR; ATTR; PALB; TBPA; Prealbumin; Transthyretin |
Product Type | Protein |
Properties | |
Source/Host | E. coli |
Crossreactivity | Human |
Biological Activity |
Activity has not been tested. |
Purity | ≥90% (SDS-PAGE) |
Formulation | Lyophilized from 20mM HEPES, pH7.0. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by AbFrontier |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Avoid freeze/thaw cycles. |
Use/Stability | After reconstitution, store at -80°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet |
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Transthyretin (TTR) , generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
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