Neurosin GST (human) (rec.)

CHF 366.00
In stock
YIF-LF-P00550.5 mgCHF 366.00
More Information
Product Details
Synonyms KLK6; SP59; Zyme; PRSS18; Neurosin; Protease M; EC=3.4.21.-; Kallikrein-6; Serine Protease 9; Serine Protease 18
Product Type Protein
Properties
Source/Host E. coli
Crossreactivity Human
Purity ≥85% (SDS-PAGE)
Concentration 1 mg/ml
Formulation Liquid in 20mM HEPES, pH 7.0, 10% Glycerol.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping DRY ICE
Short Term Storage -20°C
Long Term Storage -80°C
Handling Advice Avoid freeze/thaw cycles.
Documents
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Product Specification Sheet
Datasheet Download PDF

Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Neurosin (KLK6), one of these, is a trypsin-like protease dominantly expressed in the human brain but also in a variety of other tissues. As measured by a sensitive quantitative assay in serum and cerebrospinal fluid (CSF), it may have value as a biomarker for diagnosis and monitoring of Alzheimer’s disease (AD). It seems to be down regulated in serum and tissues of AD patients and may be involved in amyloid metabolism.

Product References

1) Akira O, et. al. Neurochemistry (2001) vol.12(7) pp.1345 -50. (General)
2) George M, et. al. Clinica Chimica Acta (2003) vol.329, pp.1-8. (General)
3) Georgios P, et. al. BBRC (2004) vol.320 pp.54-61. (General)

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